PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

44 activity records

Assay family% Degradation

Systemcell_based

ReadoutDC50

TargetGSPT1

E3Not specified

Cell lineNB4

Technologyluminescence

Detection targetprotein_degradation

Activity compounds and values

Activity records

44 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
DC50	-	=	7.2	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A007290	PGDB_C003182	PGDB_AS001663	View
DC50	-	>	1000	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A008465	PGDB_C003200	PGDB_AS001663	View
DC50	-	=	15	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A013016	PGDB_C003197	PGDB_AS001663	View
DC50	-	=	4.8	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A019557	PGDB_C003201	PGDB_AS001663	View
DC50	-	=	5.2	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A023306	PGDB_C003181	PGDB_AS001663	View
DC50	-	>	1000	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A023514	PGDB_C003177	PGDB_AS001663	View
DC50	-	>	1000	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A023986	PGDB_C003187	PGDB_AS001663	View
DC50	-	=	5.4	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A025316	PGDB_C003210	PGDB_AS001663	View
DC50	-	=	4.5	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A027210	PGDB_C003186	PGDB_AS001663	View
DC50	-	=	7.8	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A030579	PGDB_C003175	PGDB_AS001663	View
DC50	-	=	1.4	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A032969	PGDB_C003206	PGDB_AS001663	View
DC50	-	=	4.6	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A035541	PGDB_C003209	PGDB_AS001663	View
DC50	-	=	5.6	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A035583	PGDB_C003212	PGDB_AS001663	View
DC50	-	=	1.5	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A035838	PGDB_C003184	PGDB_AS001663	View
DC50	-	=	13	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A038904	PGDB_C003199	PGDB_AS001663	View
DC50	-	=	4	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A041243	PGDB_C003216	PGDB_AS001663	View
DC50	-	=	8	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A044490	PGDB_C003211	PGDB_AS001663	View
DC50	-	=	2.5	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A046918	PGDB_C003203	PGDB_AS001663	View
DC50	-	=	21	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A047030	PGDB_C003193	PGDB_AS001663	View
DC50	-	=	2	nM	-	—	GSPT1	-	NB4	WO2024222614A1	PGDB_A047485	PGDB_C003194	PGDB_AS001663	View

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