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O=C1CCC(N2Cc3cc(CN[C@@H]4CCCN(Cc5ccccc5)C4)ccc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 95 | % | - | 24 h | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A007890 | PGDB_C005887 | PGDB_AS000645 | View | |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A056352 | PGDB_C005887 | PGDB_AS000473 | View | |
| EC50 | - | = | 0.007 | uM | - | — | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A058542 | PGDB_C005887 | PGDB_AS001788 | View | |
| EC50 | - | = | 0.032 | uM | - | — | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A071963 | PGDB_C005887 | PGDB_AS002057 | View |