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Compound
PGDB_C005928
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CNC4CCN(Cc5ccccc5)C(=O)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 29 | % | - | 24 h | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A010093 | PGDB_C005928 | PGDB_AS000473 | View |
| EC50 | - | = | 1.7 | uM | - | — | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A014853 | PGDB_C005928 | PGDB_AS002057 | View |
| EC50 | - | = | 0.886 | uM | - | — | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A016006 | PGDB_C005928 | PGDB_AS001788 | View |
| EC50 | - | = | 1 | uM | - | — | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A039722 | PGDB_C005928 | PGDB_AS001788 | View |
| Dmax | - | = | 27 | % | - | 24 h | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A046489 | PGDB_C005928 | PGDB_AS000645 | View |
| Dmax | - | = | 27 | % | - | 24 h | IKZF1 | - | HEK293 | AU2022419982A1 | PGDB_A048125 | PGDB_C005928 | PGDB_AS000645 | View |
| Dmax | - | = | 27 | % | - | 24 h | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A055544 | PGDB_C005928 | PGDB_AS000473 | View |
| EC50 | - | = | 1.4 | uM | - | — | IKZF2 | - | HEK293 | AU2022419982A1 | PGDB_A060018 | PGDB_C005928 | PGDB_AS002057 | View |