Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C009986
4 activity records1 related patents
2D structure
C[C@]12COc3cc(C#N)ccc3N1CCN(Cc1ccc(COc3cccc4c3CN([C@H]3CCC(=O)NC3=O)C4=O)cc1)C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 0.0022 | uM | - | — | SALL4 | - | HT-1080 | WO2023025136A1 | PGDB_A020526 | PGDB_C009986 | PGDB_AS001426 | View |
| Dmax | - | = | 94.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A053186 | PGDB_C009986 | PGDB_AS000619 | View |
| DC50 | - | = | 0.042 | nM | - | — | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A072643 | PGDB_C009986 | PGDB_AS001276 | View |
| Dmax | - | = | 70.4 | % | Concentration series: 0.316 nM, 10 uM | 20 h | SALL4 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A075604 | PGDB_C009986 | PGDB_AS001792 | View |