Assay
PGDB_AS000619
System: cell_basedTarget: IKZF1Cell line: HT-1080
Assay context summary
Assay context
Activity compounds and values
Activity records
| Structure | Metric | Control | Relation | Value | Unit | Concentration | Time | Target | E3 | Cell line | Patent | Record ID | Compound | Assay | Details |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Dmax | - | = | 90.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A010378 | PGDB_C010001 | PGDB_AS000619 | View |
 | Dmax | - | = | 90.4 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A011406 | PGDB_C009998 | PGDB_AS000619 | View |
 | Dmax | - | = | 88.7 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A019231 | PGDB_C009996 | PGDB_AS000619 | View |
 | Dmax | - | = | 91.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A024842 | PGDB_C009993 | PGDB_AS000619 | View |
 | Dmax | - | = | 93.4 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A032960 | PGDB_C009995 | PGDB_AS000619 | View |
 | Dmax | - | = | 93.7 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A038750 | PGDB_C009989 | PGDB_AS000619 | View |
 | Dmax | - | = | 94.8 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A039339 | PGDB_C009985 | PGDB_AS000619 | View |
 | Dmax | - | = | 93.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A039395 | PGDB_C009987 | PGDB_AS000619 | View |
 | Dmax | - | = | 79.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A041482 | PGDB_C009601 | PGDB_AS000619 | View |
 | Dmax | - | = | 92.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A043657 | PGDB_C010000 | PGDB_AS000619 | View |
 | Dmax | - | = | 94.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A048243 | PGDB_C009991 | PGDB_AS000619 | View |
 | Dmax | - | = | 92.1 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A048327 | PGDB_C009999 | PGDB_AS000619 | View |
 | Dmax | - | = | 94.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A053186 | PGDB_C009986 | PGDB_AS000619 | View |
 | Dmax | - | = | 94.4 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A054318 | PGDB_C009997 | PGDB_AS000619 | View |
 | Dmax | - | = | 93.7 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A055316 | PGDB_C009992 | PGDB_AS000619 | View |
 | Dmax | - | = | 92.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A062086 | PGDB_C009990 | PGDB_AS000619 | View |
 | Dmax | - | = | 92.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A069567 | PGDB_C009994 | PGDB_AS000619 | View |
 | Dmax | - | = | 83.6 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A072700 | PGDB_C010002 | PGDB_AS000619 | View |
 | Dmax | - | = | 92.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A075032 | PGDB_C009988 | PGDB_AS000619 | View |