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Compound
PGDB_C010000
4 activity records1 related patents
2D structure
N#Cc1cnc2c(c1)OC[C@H]1CN(Cc3ccc(COc4cccc5c4CN([C@@H]4CCC(=O)NC4=O)C5=O)c(F)c3)CCN21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 46.7 | % | Concentration series: 0.316 nM, 10 uM | 20 h | SALL4 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A025271 | PGDB_C010000 | PGDB_AS001792 | View |
| Dmax | - | = | 92.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A043657 | PGDB_C010000 | PGDB_AS000619 | View |
| DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | WO2023025136A1 | PGDB_A053217 | PGDB_C010000 | PGDB_AS001426 | View |
| DC50 | - | = | 0.18 | nM | - | — | IKZF1 | CRBN | HT-1080 | WO2023025136A1 | PGDB_A071134 | PGDB_C010000 | PGDB_AS001276 | View |