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Compound
PGDB_C011709
3 activity records1 related patents
2D structure
COc1c(N2C[C@H](Nc3nnc(-c4ccc(OC(F)(F)F)cc4)o3)[C@H]2C)cc(F)c(C2CCC(=O)NC2=O)c1FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 191.2 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A020549 | PGDB_C011709 | PGDB_AS000391 | View |
| Dmax | - | = | 74 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A066121 | PGDB_C011709 | PGDB_AS002358 | View |
| Dmax | - | = | 9.5 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A072249 | PGDB_C011709 | PGDB_AS001257 | View |