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Compound
PGDB_C011714
3 activity records1 related patents
2D structure
C[C@@H]1[C@@H](Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)cc1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 273.9 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A015469 | PGDB_C011714 | PGDB_AS000391 | View |
| Dmax | - | = | 6.5 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A017976 | PGDB_C011714 | PGDB_AS001257 | View |
| Dmax | - | = | 61.7 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A073527 | PGDB_C011714 | PGDB_AS002358 | View |