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C[C@@H]1[C@@H](Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)CN1c1ccc(C2CCC(=O)NC2=O)c(F)c1C#N| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 277.2 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A014612 | PGDB_C011715 | PGDB_AS000391 | View | |
| Dmax | - | = | 7 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A052827 | PGDB_C011715 | PGDB_AS001257 | View | |
| Dmax | - | = | 65.9 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A076421 | PGDB_C011715 | PGDB_AS002358 | View |