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Compound
PGDB_C011727
3 activity records1 related patents
2D structure
COc1ccc(-c2nnc(N[C@H]3CN(c4cc(Cl)c(C5CCC(=O)NC5=O)c(Cl)c4)[C@@H]3C)o2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 458.5 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A017036 | PGDB_C011727 | PGDB_AS000391 | View |
| Dmax | - | = | 12 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A048015 | PGDB_C011727 | PGDB_AS001257 | View |
| Dmax | - | = | 59.7 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A072789 | PGDB_C011727 | PGDB_AS002358 | View |