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Compound
PGDB_C011749
3 activity records1 related patents
2D structure
CC1(Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)CN(c2cc(F)c(C3CCC(=O)NC3=O)c(F)c2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 24.6 | nM | - | — | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A011084 | PGDB_C011749 | PGDB_AS000391 | View |
| Dmax | - | = | 89.1 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025224249A1 | PGDB_A057817 | PGDB_C011749 | PGDB_AS001257 | View |
| Dmax | - | = | 94 | % | - | 24 h | CDK2 | - | HEK293 | WO2025224249A1 | PGDB_A066208 | PGDB_C011749 | PGDB_AS002358 | View |