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Compound
PGDB_C012309
8 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)C3=C(C2=O)N(Cc2nc(-c4cccc(-c5cnccn5)c4)ns2)CCC3)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A010084 | PGDB_C012309 | PGDB_AS001769 | View |
| EC50 | - | = | 100-1000 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A018328 | PGDB_C012309 | PGDB_AS000738 | View |
| EC50 | - | = | 100-1000 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A027109 | PGDB_C012309 | PGDB_AS000738 | View |
| EC50 | - | = | 10-100 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A034327 | PGDB_C012309 | PGDB_AS002152 | View |
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A034445 | PGDB_C012309 | PGDB_AS001094 | View |
| EC50 | - | = | 10-100 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A039779 | PGDB_C012309 | PGDB_AS002152 | View |
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A043364 | PGDB_C012309 | PGDB_AS001769 | View |
| Emax | - | = | 50-120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A075632 | PGDB_C012309 | PGDB_AS001094 | View |