Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C012385
4 activity records1 related patents
2D structure
Cc1cc(-c2cccc(-c3nsc(CN4CCCC5=C4C(=O)N(C4CCC(=O)NC4=O)C5=O)n3)c2F)ccn1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 10-100 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A014532 | PGDB_C012385 | PGDB_AS002152 | View |
| Emax | - | = | 50-120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A027880 | PGDB_C012385 | PGDB_AS001769 | View |
| Emax | - | < | 50 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A069809 | PGDB_C012385 | PGDB_AS001094 | View |
| EC50 | - | = | 100-1000 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A077562 | PGDB_C012385 | PGDB_AS000738 | View |