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Compound
PGDB_C014259
12 activity records1 related patents
2D structure
O=C1CCN(N2Cc3cc(CNC45CC6CC(CC(O)(C6)C4)C5)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 20-40 | % | 500 nM | - | - | - | H292 | WO2024245444A1 | PGDB_A024493 | PGDB_C014259 | PGDB_AS000415 | View |
| % Inhibition | - | = | 18-25 | % | 10 nM | - | - | - | MDA-MB-231 | WO2024245444A1 | PGDB_A024952 | PGDB_C014259 | PGDB_AS002156 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2024245444A1 | PGDB_A028583 | PGDB_C014259 | PGDB_AS002298 | View |
| % Inhibition | - | = | 30-40 | % | 500 nM | - | - | - | H2228 | WO2024245444A1 | PGDB_A029087 | PGDB_C014259 | PGDB_AS000051 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2024245444A1 | PGDB_A032020 | PGDB_C014259 | PGDB_AS001967 | View |
| % Inhibition | - | = | 20-40 | % | 10 nM | - | - | - | H292 | WO2024245444A1 | PGDB_A033031 | PGDB_C014259 | PGDB_AS001605 | View |
| % Inhibition | - | = | 25-30 | % | 10 nM | - | - | - | H2228 | WO2024245444A1 | PGDB_A039167 | PGDB_C014259 | PGDB_AS001356 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2024245444A1 | PGDB_A041520 | PGDB_C014259 | PGDB_AS000969 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2024245444A1 | PGDB_A057611 | PGDB_C014259 | PGDB_AS001137 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2024245444A1 | PGDB_A065164 | PGDB_C014259 | PGDB_AS000339 | View |
| % Inhibition | - | = | 25-40 | % | 500 nM | - | - | - | MDA-MB-231 | WO2024245444A1 | PGDB_A074761 | PGDB_C014259 | PGDB_AS002131 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2024245444A1 | PGDB_A076392 | PGDB_C014259 | PGDB_AS001444 | View |