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Compound
PGDB_C019309
7 activity records1 related patents
2D structure
Cc1nc(N2CCN(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)c2ccsc2n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 0.5 | uM | - | — | CRBN | CRBN | - | WO2025016359A1 | PGDB_A010117 | PGDB_C019309 | PGDB_AS001897 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025016359A1 | PGDB_A011902 | PGDB_C019309 | PGDB_AS002465 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2025016359A1 | PGDB_A032094 | PGDB_C019309 | PGDB_AS000700 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2025016359A1 | PGDB_A045548 | PGDB_C019309 | PGDB_AS002547 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2025016359A1 | PGDB_A046949 | PGDB_C019309 | PGDB_AS001760 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025016359A1 | PGDB_A069621 | PGDB_C019309 | PGDB_AS001647 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025016359A1 | PGDB_A071195 | PGDB_C019309 | PGDB_AS000593 | View |