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Compound
PGDB_C019359
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCN(c5ccnc(Br)c5F)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 0.5 | uM | - | — | CRBN | CRBN | - | WO2025016359A1 | PGDB_A009992 | PGDB_C019359 | PGDB_AS001897 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025016359A1 | PGDB_A011895 | PGDB_C019359 | PGDB_AS000593 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2025016359A1 | PGDB_A019377 | PGDB_C019359 | PGDB_AS000700 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2025016359A1 | PGDB_A022730 | PGDB_C019359 | PGDB_AS002547 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025016359A1 | PGDB_A023596 | PGDB_C019359 | PGDB_AS001647 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2025016359A1 | PGDB_A035963 | PGDB_C019359 | PGDB_AS001760 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025016359A1 | PGDB_A064475 | PGDB_C019359 | PGDB_AS002465 | View |