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Compound
PGDB_C019370
7 activity records1 related patents
2D structure
Cc1sc2ncnc(C3CCN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)c2c1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2025016359A1 | PGDB_A008728 | PGDB_C019370 | PGDB_AS001760 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2025016359A1 | PGDB_A018283 | PGDB_C019370 | PGDB_AS002547 | View |
| IC50 | - | <= | 0.5 | uM | - | — | CRBN | CRBN | - | WO2025016359A1 | PGDB_A019575 | PGDB_C019370 | PGDB_AS001897 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025016359A1 | PGDB_A028782 | PGDB_C019370 | PGDB_AS001647 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2025016359A1 | PGDB_A039433 | PGDB_C019370 | PGDB_AS000700 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025016359A1 | PGDB_A055421 | PGDB_C019370 | PGDB_AS002465 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025016359A1 | PGDB_A068914 | PGDB_C019370 | PGDB_AS000593 | View |