Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C019482
7 activity records1 related patents
2D structure
CC1(C)C2CCC1(CS(=O)(=O)NCc1ccc3c(c1)CN(C1CCC(=O)NC1=O)C3=O)C(=O)C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025016359A1 | PGDB_A007418 | PGDB_C019482 | PGDB_AS002465 | View |
| IC50 | - | = | 0.5-1 | uM | - | — | CRBN | CRBN | - | WO2025016359A1 | PGDB_A007871 | PGDB_C019482 | PGDB_AS001897 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025016359A1 | PGDB_A037761 | PGDB_C019482 | PGDB_AS001647 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2025016359A1 | PGDB_A045826 | PGDB_C019482 | PGDB_AS000700 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025016359A1 | PGDB_A052605 | PGDB_C019482 | PGDB_AS000593 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2025016359A1 | PGDB_A067177 | PGDB_C019482 | PGDB_AS001760 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2025016359A1 | PGDB_A074442 | PGDB_C019482 | PGDB_AS002547 | View |