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CC(C)(C(=O)NCc1cc(Cl)c([C@H]2CCC(=O)NC2=O)c(Cl)c1)c1ncc(C#N)cn1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | <= | 100 | nM | - | — | - | - | CAL-51 | KR20260041885A | PGDB_A009445 | PGDB_C020326 | PGDB_AS000761 | View | |
| EC50 | - | > | 1000 | nM | - | — | - | - | - | KR20260041885A | PGDB_A010111 | PGDB_C020326 | PGDB_AS000595 | View | |
| Dmax | - | > | 75 | % | Concentration context: various concentrations | 24 h | - | - | CAL-51 | KR20260041885A | PGDB_A024659 | PGDB_C020326 | PGDB_AS000078 | View | |
| DC50 | - | = | 53 | nM | - | — | NEK7 | - | CAL-51 | WO2025024521A1 | PGDB_A050331 | PGDB_C020326 | PGDB_AS001365 | View | |
| Dmax | - | = | 90 | % | Concentration series: 1 uM, 0.05 nM | 24 h | NEK7 | - | CAL-51 | WO2025024521A1 | PGDB_A058248 | PGDB_C020326 | PGDB_AS002061 | View | |
| EC50 | - | = | 10 | uM | - | — | CRBN | CRBN | - | WO2025024521A1 | PGDB_A062130 | PGDB_C020326 | PGDB_AS001033 | View |