Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C020478
7 activity records1 related patents
2D structure
CCC(=O)Nc1ccc(COC(C)N(C)CCOCC2(c3ccc(C(C)NCc4ccc5c6c(cccc46)C(=O)N5C4CCC(=O)NC4=O)cc3Cl)CC2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A009253 | PGDB_C020478 | PGDB_AS002258 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A022732 | PGDB_C020478 | PGDB_AS000299 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A026381 | PGDB_C020478 | PGDB_AS002143 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A039263 | PGDB_C020478 | PGDB_AS002143 | View |
| IC50 | - | <= | 0.5 | nM | - | — | GSPT1 | - | HCC1569 | WO2025162410A1 | PGDB_A040482 | PGDB_C020478 | PGDB_AS001676 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A069907 | PGDB_C020478 | PGDB_AS002258 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A074927 | PGDB_C020478 | PGDB_AS000299 | View |