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Compound
PGDB_C020481
7 activity records1 related patents
2D structure
CN(CCOCC1(c2ccc(NC(=O)NCc3ccc4c5c(cccc35)C(=O)N4C3CCC(=O)NC3=O)cc2C(=O)O)CC1)C(C#N)OCc1ccc(NC(Cl)CO)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A007505 | PGDB_C020481 | PGDB_AS002143 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A028713 | PGDB_C020481 | PGDB_AS002258 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A031661 | PGDB_C020481 | PGDB_AS000299 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A038489 | PGDB_C020481 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A048476 | PGDB_C020481 | PGDB_AS002258 | View |
| IC50 | - | <= | 0.5 | nM | - | — | GSPT1 | - | HCC1569 | WO2025162410A1 | PGDB_A053969 | PGDB_C020481 | PGDB_AS001676 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A068738 | PGDB_C020481 | PGDB_AS002143 | View |