Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C020497
7 activity records1 related patents
2D structure
COc1cc(C(=O)NCc2ccc3c4c(cccc24)C(=O)N3C2CCC(=O)NC2=O)ccc1C(C)(C)COCCN(C)C(=O)c1ccc(N)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A010430 | PGDB_C020497 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A018465 | PGDB_C020497 | PGDB_AS002258 | View |
| IC50 | - | <= | 0.5 | nM | - | — | GSPT1 | - | HCC1569 | WO2025162410A1 | PGDB_A021310 | PGDB_C020497 | PGDB_AS001676 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A022597 | PGDB_C020497 | PGDB_AS002143 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A022681 | PGDB_C020497 | PGDB_AS002143 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A050317 | PGDB_C020497 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A059751 | PGDB_C020497 | PGDB_AS002258 | View |