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Compound
PGDB_C020499
7 activity records1 related patents
2D structure
CN(CCCCCc1ccc(C(=O)NCc2ccc3c4c(cccc24)C(=O)N3C2CCC(=O)NC2=O)cc1Cl)C(=O)c1ccc(NC(=O)CO)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A007633 | PGDB_C020499 | PGDB_AS002143 | View |
| IC50 | - | <= | 0.5 | nM | - | — | GSPT1 | - | HCC1569 | WO2025162410A1 | PGDB_A030933 | PGDB_C020499 | PGDB_AS001676 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A031151 | PGDB_C020499 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A031927 | PGDB_C020499 | PGDB_AS002258 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A044187 | PGDB_C020499 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A068790 | PGDB_C020499 | PGDB_AS002258 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A073929 | PGDB_C020499 | PGDB_AS002143 | View |