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Compound
PGDB_C020502
7 activity records1 related patents
2D structure
COc1cc(C(=O)NCc2ccc3c4c(cccc24)C(=O)N3C2CCC(=O)NC2=O)ccc1C1(COCCN(C)C(=O)OCc2ccc(NC(=O)CO)cc2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A020480 | PGDB_C020502 | PGDB_AS002143 | View |
| IC50 | - | <= | 0.5 | nM | - | — | GSPT1 | - | HCC1569 | WO2025162410A1 | PGDB_A020690 | PGDB_C020502 | PGDB_AS001676 | View |
| IC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | HEK293T | WO2025162410A1 | PGDB_A024321 | PGDB_C020502 | PGDB_AS002143 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A028802 | PGDB_C020502 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A046723 | PGDB_C020502 | PGDB_AS002258 | View |
| Selectivity index | 293T/HCC569 | = | 10-100 | fold | - | — | - | - | - | WO2025162410A1 | PGDB_A067273 | PGDB_C020502 | PGDB_AS000299 | View |
| EC50 | - | = | <= 0.5 | nM | - | — | GSPT1 | - | - | WO2025162410A1 | PGDB_A074418 | PGDB_C020502 | PGDB_AS002258 | View |