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Compound
PGDB_C024254
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CC5CN(CCCCCCCNC67CC8CC(CC(C8)C6)C7)CC5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 20-30 | % | 10 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A037603 | PGDB_C024254 | PGDB_AS000160 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A041240 | PGDB_C024254 | PGDB_AS002133 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A047812 | PGDB_C024254 | PGDB_AS000702 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A060635 | PGDB_C024254 | PGDB_AS002540 | View |
| % Inhibition | - | = | 60-70 | % | 500 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A067171 | PGDB_C024254 | PGDB_AS002558 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A068960 | PGDB_C024254 | PGDB_AS001902 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A076803 | PGDB_C024254 | PGDB_AS002550 | View |