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Compound
PGDB_C024263
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(NN4CCN(Cc5ccc(CN6CCCCC6)cc5)CC4)cccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A013677 | PGDB_C024263 | PGDB_AS001561 | View |
| % Inhibition | - | = | 40-50 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A021223 | PGDB_C024263 | PGDB_AS001155 | View |
| % Inhibition | - | = | 20-30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A021414 | PGDB_C024263 | PGDB_AS002324 | View |
| % Inhibition | - | = | 20-30 | % | 10 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A030770 | PGDB_C024263 | PGDB_AS000160 | View |
| % Inhibition | - | > | 30 | % | 1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A051646 | PGDB_C024263 | PGDB_AS002304 | View |
| % Inhibition | - | = | 10-20 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A061429 | PGDB_C024263 | PGDB_AS002133 | View |
| % Inhibition | - | = | 60-70 | % | 500 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A065393 | PGDB_C024263 | PGDB_AS002558 | View |
| % Inhibition | - | = | 53-60 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A075593 | PGDB_C024263 | PGDB_AS002540 | View |