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Compound
PGDB_C024264
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CC5CN(Cc6ccc(CN7CCCCC7)cc6)CC5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 10-20 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A011750 | PGDB_C024264 | PGDB_AS001561 | View |
| % Inhibition | - | = | 50-60 | % | 10 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A050182 | PGDB_C024264 | PGDB_AS000160 | View |
| % Inhibition | - | = | 60-70 | % | 500 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A052614 | PGDB_C024264 | PGDB_AS002558 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A057812 | PGDB_C024264 | PGDB_AS002540 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A064433 | PGDB_C024264 | PGDB_AS002133 | View |
| % Inhibition | - | = | 60-70 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A069301 | PGDB_C024264 | PGDB_AS001155 | View |