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Compound
PGDB_C024266
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(N(C(c4ccccc4)c4cccnc4)N4CC5CN(C(c6ccccc6)c6cccnc6)CC5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 50-60 | % | 500 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A018174 | PGDB_C024266 | PGDB_AS002558 | View |
| % Inhibition | - | = | 80-100 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A037037 | PGDB_C024266 | PGDB_AS002540 | View |
| % Inhibition | - | = | 70-80 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A040754 | PGDB_C024266 | PGDB_AS002133 | View |
| % Inhibition | - | = | 50-60 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A045168 | PGDB_C024266 | PGDB_AS001561 | View |
| % Inhibition | - | = | 50-60 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A060124 | PGDB_C024266 | PGDB_AS001155 | View |
| % Inhibition | - | = | 20-30 | % | 10 nM | 96 h | IKZF3 | - | TMD8 | WO2025162225A1 | PGDB_A070463 | PGDB_C024266 | PGDB_AS000160 | View |