Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C024487
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CCN(CC5=C(c6ccc(Cl)cc6)CCC(F)(F)C5)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 20-30 | % | 10 nM | 96 h | IKZF3 | - | H196 | WO2025162225A1 | PGDB_A007897 | PGDB_C024487 | PGDB_AS001140 | View |
| % Inhibition | - | = | 20-30 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A020117 | PGDB_C024487 | PGDB_AS002133 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A052649 | PGDB_C024487 | PGDB_AS002540 | View |
| % Inhibition | - | = | 50-60 | % | 500 nM | 96 h | IKZF3 | - | H196 | WO2025162225A1 | PGDB_A071956 | PGDB_C024487 | PGDB_AS000866 | View |