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Compound
PGDB_C025966
5 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(CN4CCN(c5ccc(-n6cc(NC(=O)c7coc(-c8ccnc(NCC(F)(F)F)c8)n7)c(C(F)F)n6)cc5)CC4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-500 | nM | - | — | IRAK4 | - | LNCaP | CN116239566A | PGDB_A016945 | PGDB_C025966 | PGDB_AS000964 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | IRAK4 | - | Jurkat | CN116239566A | PGDB_A029313 | PGDB_C025966 | PGDB_AS000478 | View |
| IC50 | - | = | 500-1000 | nM | - | — | IRAK4 | - | MM.1R | CN116239566A | PGDB_A031820 | PGDB_C025966 | PGDB_AS000191 | View |
| IC50 | - | = | 500-1000 | nM | - | — | IRAK4 | - | Hep3B2.7-1 | CN116239566A | PGDB_A035721 | PGDB_C025966 | PGDB_AS000953 | View |
| IC50 | - | = | 50-100 | nM | - | — | IRAK4 | - | Kasumi-1 | CN116239566A | PGDB_A050637 | PGDB_C025966 | PGDB_AS001230 | View |