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Compound
PGDB_C029774
10 activity records1 related patents
2D structure
COc1cc(O[C@H]2C(C)(C)[C@H](NC(=O)c3ccc(N4CCC(CN5CCN6c7ccc(C8CCC(=O)NC8=O)cc7OCC[C@H]6C5)CC4)cc3)C2(C)C)ccc1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 76 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000309 | PGDB_C029774 | PGDB_AS002389 | View |
| % Degradation | - | = | 77 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000721 | PGDB_C029774 | PGDB_AS002389 | View |
| % Degradation | - | = | 59 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000953 | PGDB_C029774 | PGDB_AS002463 | View |
| % Degradation | - | = | 77 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A003427 | PGDB_C029774 | PGDB_AS001354 | View |
| % Degradation | - | = | 87 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A003650 | PGDB_C029774 | PGDB_AS001838 | View |
| IC50 | - | = | 0.006 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A003868 | PGDB_C029774 | PGDB_AS000271 | View |
| % Degradation | - | = | 87 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A004590 | PGDB_C029774 | PGDB_AS001354 | View |
| % Degradation | - | = | 88 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A006378 | PGDB_C029774 | PGDB_AS001838 | View |
| % Degradation | - | = | 47 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A006948 | PGDB_C029774 | PGDB_AS002463 | View |
| IC50 | - | = | 0.008 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A079004 | PGDB_C029774 | PGDB_AS000271 | View |