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Compound
PGDB_C030288
11 activity records1 related patents
2D structure
Nc1nnc(-c2ccccc2O)cc1N1CC2CCC(C1)N2c1ncc(C2CCN(Cc3cc4c(cc3F)C(=O)N(C3CCC(=O)NC3=O)C4)CC2)cn1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA2 | - | MV-4-11 | WO2026061475A1 | PGDB_A000083 | PGDB_C030288 | PGDB_AS002335 | View |
| IC50 | - | = | 20-30 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A001707 | PGDB_C030288 | PGDB_AS000282 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A005550 | PGDB_C030288 | PGDB_AS001031 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA4 | - | MV-4-11 | WO2026061475A1 | PGDB_A006805 | PGDB_C030288 | PGDB_AS002340 | View |
| IC50 | - | = | 700-900 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A081268 | PGDB_C030288 | PGDB_AS000179 | View |
| % Inhibition | - | = | 53-60 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A081678 | PGDB_C030288 | PGDB_AS000662 | View |