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Compound
PGDB_C030398
11 activity records1 related patents
2D structure
Nc1nnc(-c2cc(F)ccc2O)cc1N1CCN(c2ccc(N3CCC(CN4CCCC(Sc5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)CC4)CC3)cc2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10-20 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A001075 | PGDB_C030398 | PGDB_AS000282 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A001715 | PGDB_C030398 | PGDB_AS001031 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA2 | - | MV-4-11 | WO2026061475A1 | PGDB_A001830 | PGDB_C030398 | PGDB_AS002335 | View |
| IC50 | - | = | 100-200 | nM | - | — | - | - | BT549 | WO2026061475A1 | PGDB_A079205 | PGDB_C030398 | PGDB_AS002259 | View |
| IC50 | - | = | 100-200 | nM | - | — | - | - | A549 | WO2026061475A1 | PGDB_A080006 | PGDB_C030398 | PGDB_AS000757 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA4 | - | MV-4-11 | WO2026061475A1 | PGDB_A081277 | PGDB_C030398 | PGDB_AS002340 | View |
| IC50 | - | = | 100-200 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A081286 | PGDB_C030398 | PGDB_AS000179 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A081674 | PGDB_C030398 | PGDB_AS000662 | View |