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Compound
PGDB_C030424
9 activity records1 related patents
2D structure
O=C1CCN(c2cccc(CN3CCN(c4ccc5cc(-c6ccccc6O)nnc5c4)CC3)c2)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10-20 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A002079 | PGDB_C030424 | PGDB_AS000179 | View |
| IC50 | - | = | 50-100 | nM | - | — | - | - | BT549 | WO2026061475A1 | PGDB_A004560 | PGDB_C030424 | PGDB_AS002259 | View |
| IC50 | - | = | 50-100 | nM | - | — | - | - | H2126 | WO2026061475A1 | PGDB_A004588 | PGDB_C030424 | PGDB_AS001417 | View |
| % Inhibition | - | = | 60-70 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A006395 | PGDB_C030424 | PGDB_AS001031 | View |
| IC50 | - | = | 200-500 | nM | - | — | - | - | A549 | WO2026061475A1 | PGDB_A078258 | PGDB_C030424 | PGDB_AS000757 | View |
| IC50 | - | <= | 1 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A080105 | PGDB_C030424 | PGDB_AS000282 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A080555 | PGDB_C030424 | PGDB_AS000662 | View |