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Compound
PGDB_C030850
6 activity records1 related patents
2D structure
Cc1cc(N)nc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)c1OC(F)FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 11 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000373 | PGDB_C030850 | PGDB_AS000804 | View |
| Dmax | - | = | 9 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A001629 | PGDB_C030850 | PGDB_AS000982 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A002115 | PGDB_C030850 | PGDB_AS000302 | View |
| DC50 | - | = | 296 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A003649 | PGDB_C030850 | PGDB_AS001885 | View |
| Dmax | - | = | 76 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A079655 | PGDB_C030850 | PGDB_AS000354 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A079810 | PGDB_C030850 | PGDB_AS000910 | View |