Assay

PGDB_AS001885

System: cell_basedTarget: IKZF2Cell line: Jurkat
Assay context summary

Assay context

339 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF2
E3Not specified
Cell lineJurkat
OrganismHomo sapiens
Technologyflow_cytometry
Detection targetprotein_degradation
Activity compounds and values

Activity records

339 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C030846
DC50-=52nM-—IKZF2-JurkatWO2026080794A1PGDB_A000007PGDB_C030846PGDB_AS001885View
2D structure for PGDB_C030910
DC50-=10nM-—IKZF2-JurkatWO2026080794A1PGDB_A000038PGDB_C030910PGDB_AS001885View
2D structure for PGDB_C031127
DC50-=8nM-—IKZF2-JurkatWO2026080794A1PGDB_A000056PGDB_C031127PGDB_AS001885View
2D structure for PGDB_C031001
DC50-=26nM-—IKZF2-JurkatWO2026080794A1PGDB_A000085PGDB_C031001PGDB_AS001885View
2D structure for PGDB_C030974
DC50-=29nM-—IKZF2-JurkatWO2026080794A1PGDB_A000091PGDB_C030974PGDB_AS001885View
2D structure for PGDB_C030862
DC50-=231nM-—IKZF2-JurkatWO2026080794A1PGDB_A000094PGDB_C030862PGDB_AS001885View
2D structure for PGDB_C030952
DC50-=2nM-—IKZF2-JurkatWO2026080794A1PGDB_A000103PGDB_C030952PGDB_AS001885View
2D structure for PGDB_C030981
DC50-=6nM-—IKZF2-JurkatWO2026080794A1PGDB_A000112PGDB_C030981PGDB_AS001885View
2D structure for PGDB_C031077
DC50-=45nM-—IKZF2-JurkatWO2026080794A1PGDB_A000178PGDB_C031077PGDB_AS001885View
2D structure for PGDB_C030765
DC50-=320nM-—IKZF2-JurkatWO2026080794A1PGDB_A000182PGDB_C030765PGDB_AS001885View
2D structure for PGDB_C030928
DC50-=9nM-—IKZF2-JurkatWO2026080794A1PGDB_A000200PGDB_C030928PGDB_AS001885View
2D structure for PGDB_C030931
DC50-=235nM-—IKZF2-JurkatWO2026080794A1PGDB_A000226PGDB_C030931PGDB_AS001885View
2D structure for PGDB_C030830
DC50-=10nM-—IKZF2-JurkatWO2026080794A1PGDB_A000267PGDB_C030830PGDB_AS001885View
2D structure for PGDB_C030800
DC50-=59nM-—IKZF2-JurkatWO2026080794A1PGDB_A000278PGDB_C030800PGDB_AS001885View
2D structure for PGDB_C031037
DC50-=14nM-—IKZF2-JurkatWO2026080794A1PGDB_A000337PGDB_C031037PGDB_AS001885View
2D structure for PGDB_C030841
DC50-=43nM-—IKZF2-JurkatWO2026080794A1PGDB_A000386PGDB_C030841PGDB_AS001885View
2D structure for PGDB_C031035
DC50-=170nM-—IKZF2-JurkatWO2026080794A1PGDB_A000414PGDB_C031035PGDB_AS001885View
2D structure for PGDB_C030965
DC50-=4nM-—IKZF2-JurkatWO2026080794A1PGDB_A000460PGDB_C030965PGDB_AS001885View
2D structure for PGDB_C031022
DC50-=56nM-—IKZF2-JurkatWO2026080794A1PGDB_A000461PGDB_C031022PGDB_AS001885View
2D structure for PGDB_C030807
DC50-=235nM-—IKZF2-JurkatWO2026080794A1PGDB_A000490PGDB_C030807PGDB_AS001885View
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