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Nc1nc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)ccc1CN1CCC2(CCCOC2)CC1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 77 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000301 | PGDB_C030919 | PGDB_AS000804 | View | |
| DC50 | - | = | 420 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A002890 | PGDB_C030919 | PGDB_AS000302 | View | |
| DC50 | - | = | 1208 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A003939 | PGDB_C030919 | PGDB_AS000910 | View | |
| Dmax | - | = | 93 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A005786 | PGDB_C030919 | PGDB_AS000354 | View | |
| Dmax | - | = | 65 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A080067 | PGDB_C030919 | PGDB_AS000982 | View | |
| DC50 | - | = | 16 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A080703 | PGDB_C030919 | PGDB_AS001885 | View |