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Compound
PGDB_C030949
6 activity records1 related patents
2D structure
Nc1cc(CN2CCCC2)cc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 63 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A000464 | PGDB_C030949 | PGDB_AS000982 | View |
| DC50 | - | = | 77 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A002540 | PGDB_C030949 | PGDB_AS000910 | View |
| DC50 | - | = | 1 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A004887 | PGDB_C030949 | PGDB_AS001885 | View |
| DC50 | - | = | 16 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A078407 | PGDB_C030949 | PGDB_AS000302 | View |
| Dmax | - | = | 93 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A080946 | PGDB_C030949 | PGDB_AS000354 | View |
| Dmax | - | = | 69 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A081024 | PGDB_C030949 | PGDB_AS000804 | View |