Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C031048
6 activity records1 related patents
2D structure
Nc1nc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)cc2c1OC(F)(F)O2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 61 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000034 | PGDB_C031048 | PGDB_AS000804 | View |
| Dmax | - | = | 94 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A002699 | PGDB_C031048 | PGDB_AS000354 | View |
| DC50 | - | = | 18 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A003589 | PGDB_C031048 | PGDB_AS001885 | View |
| DC50 | - | = | 3336 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A078031 | PGDB_C031048 | PGDB_AS000910 | View |
| Dmax | - | = | 63 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A080287 | PGDB_C031048 | PGDB_AS000982 | View |
| DC50 | - | = | 1034 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A080778 | PGDB_C031048 | PGDB_AS000302 | View |