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Compound
PGDB_C031077
6 activity records1 related patents
2D structure
CNc1nc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)c(OC)c2nn(C)nc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 45 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A000178 | PGDB_C031077 | PGDB_AS001885 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A002376 | PGDB_C031077 | PGDB_AS000302 | View |
| Dmax | - | = | 88 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A002757 | PGDB_C031077 | PGDB_AS000354 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A003837 | PGDB_C031077 | PGDB_AS000910 | View |
| Dmax | - | = | -2 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A006770 | PGDB_C031077 | PGDB_AS000982 | View |
| Dmax | - | = | 2 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A079649 | PGDB_C031077 | PGDB_AS000804 | View |