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Compound
PGDB_C031217
5 activity records1 related patents
2D structure
Cc1cnc(C(C)(C)C(=O)NCc2cc(Cl)c(N3CCC(=O)NC3=O)c(Cl)c2)nc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.108 | uM | - | — | CASP1 | - | monocyte-derivedmacrophages | WO2026099466A1 | PGDB_A000180 | PGDB_C031217 | PGDB_AS002042 | View |
| EC50 | - | = | 3.9 | uM | - | — | CRBN | CRBN | - | WO2026099466A1 | PGDB_A004593 | PGDB_C031217 | PGDB_AS002171 | View |
| IC50 | - | = | 0.1136 | uM | - | — | NEK7 | - | monocyte-derivedmacrophages | WO2026099466A1 | PGDB_A005015 | PGDB_C031217 | PGDB_AS001541 | View |
| DC50 | - | = | 105 | nM | - | — | NEK7 | - | CAL-51 | WO2026099466A1 | PGDB_A005823 | PGDB_C031217 | PGDB_AS000897 | View |
| Dmax | - | = | 74 | % | Concentration series: 1 uM, 0.05 nM | - | NEK7 | - | CAL-51 | WO2026099466A1 | PGDB_A081853 | PGDB_C031217 | PGDB_AS000358 | View |