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Compound
PGDB_C031712
6 activity records1 related patents
2D structure
Cc1cnc(N(CC=C(F)F)c2ccc(-c3cccc(C4CCC(=O)NC4=O)c3Cl)cc2)nc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114367A1 | PGDB_A000177 | PGDB_C031712 | PGDB_AS002534 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primary T cells | WO2026114367A1 | PGDB_A001032 | PGDB_C031712 | PGDB_AS000754 | View |
| DC50 | - | <= | 20 | nM | - | — | VAV1 | - | - | WO2026114367A1 | PGDB_A002322 | PGDB_C031712 | PGDB_AS000190 | View |
| % Degradation | - | > | 50 | % | 10 nM | - | VAV1 | - | Jurkat | WO2026114367A1 | PGDB_A005636 | PGDB_C031712 | PGDB_AS001673 | View |
| DC50 | - | <= | 20 | nM | - | — | VAV1 | - | primary_human_blood | WO2026114367A1 | PGDB_A079482 | PGDB_C031712 | PGDB_AS001692 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114367A1 | PGDB_A080524 | PGDB_C031712 | PGDB_AS000152 | View |