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Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | DC50 | - | = | 2.3 | nM | - | — | VAV1 | - | - | WO2026051943A1 | PGDB_A000001 | PGDB_C029684 | PGDB_AS001440 | View |
 | IC50 | - | = | 100-200 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A000002 | PGDB_C030428 | PGDB_AS000179 | View |
 | IC50 | - | = | 3.8 | nM | - | — | - | CRBN | GP5d | WO2026114958A1 | PGDB_A000003 | PGDB_C031967 | PGDB_AS002003 | View |
 | Dmax | - | = | 93 | % | Concentration series: 1µM to 0.05nM | - | NEK7 | - | CAL-51 | WO2026099466A1 | PGDB_A000004 | PGDB_C031206 | PGDB_AS000358 | View |
 | DC50 | - | = | 10000 | nM | - | — | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A000005 | PGDB_C032272 | PGDB_AS001413 | View |
 | % Degradation | - | = | 65 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000006 | PGDB_C029932 | PGDB_AS002389 | View |
 | DC50 | - | = | 52 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A000007 | PGDB_C030846 | PGDB_AS001885 | View |
 | DC50 | - | = | 10000 | nM | - | — | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A000008 | PGDB_C032265 | PGDB_AS001413 | View |
 | EC50 | - | = | 1.2 | uM | - | — | CRBN | CRBN | - | WO2026099466A1 | PGDB_A000010 | PGDB_C031256 | PGDB_AS002171 | View |
 | IC50 | - | <= | 1 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A000011 | PGDB_C030373 | PGDB_AS000179 | View |
 | % Degradation | - | = | 96 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A000012 | PGDB_C029984 | PGDB_AS001838 | View |
 | % Degradation | - | = | 79 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A000013 | PGDB_C029769 | PGDB_AS001838 | View |
 | IC50 | - | = | 1-5 | nM | - | — | STAT6 | - | - | WO2026107062A1 | PGDB_A000014 | PGDB_C031669 | PGDB_AS000253 | View |
 | DC50 | - | = | 5 | nM | - | — | VAV1 | - | - | WO2026051943A1 | PGDB_A000016 | PGDB_C029462 | PGDB_AS001440 | View |
 | % Degradation | - | = | 70 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A000017 | PGDB_C029736 | PGDB_AS001354 | View |
 | Dmax | - | = | 92 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A000018 | PGDB_C030788 | PGDB_AS000354 | View |
 | EC50 | - | = | 2.7 | uM | - | — | CRBN | CRBN | - | WO2026099466A1 | PGDB_A000019 | PGDB_C031289 | PGDB_AS002171 | View |
 | IC50 | - | = | 0.53 | nM | - | — | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000020 | PGDB_C029952 | PGDB_AS000195 | View |
 | % Inhibition | - | = | 60-70 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A000021 | PGDB_C030500 | PGDB_AS000662 | View |
 | DC50 | - | = | 92 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000023 | PGDB_C030999 | PGDB_AS000302 | View |
 | % Inhibition | - | = | 20-30 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A000024 | PGDB_C030285 | PGDB_AS000662 | View |
| % Degradation | - | = | 93 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000025 | PGDB_C029736 | PGDB_AS002389 | View |
 | DC50 | - | = | 2 | nM | - | — | VAV1 | - | - | WO2026119120A1 | PGDB_A000026 | PGDB_C032005 | PGDB_AS001984 | View |
 | Dmax | - | = | 50 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A000027 | PGDB_C030781 | PGDB_AS000982 | View |
 | IC50 | - | = | 0.0065 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000029 | PGDB_C029789 | PGDB_AS000481 | View |