PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

55 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

Cell lineJurkat

OrganismHomo sapiens

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

55 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A009940	PGDB_C001347	PGDB_AS000601	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A010469	PGDB_C001305	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A012132	PGDB_C001330	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A016854	PGDB_C001354	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A017412	PGDB_C001355	PGDB_AS000601	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A020731	PGDB_C001352	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A021779	PGDB_C001310	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A022118	PGDB_C001351	PGDB_AS000601	View
% Degradation	-	<=	30	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A023140	PGDB_C001359	PGDB_AS000601	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A023952	PGDB_C001345	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A027827	PGDB_C001340	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A028906	PGDB_C001358	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A029340	PGDB_C001360	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A030642	PGDB_C001331	PGDB_AS000601	View
% Degradation	-	=	30-50	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A031597	PGDB_C001334	PGDB_AS000601	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A034101	PGDB_C001342	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A034870	PGDB_C001313	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A034948	PGDB_C001333	PGDB_AS000601	View
% Degradation	-	=	90-100	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A035126	PGDB_C001326	PGDB_AS000601	View
% Degradation	-	=	70-90	%	1 uM	24 h	GSPT1	-	Jurkat	KR20250075510A	PGDB_A035591	PGDB_C001336	PGDB_AS000601	View

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