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Compound
PGDB_C001355
8 activity records2 related patents
2D structure
Nc1ccc(C(=O)c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A015000 | PGDB_C001355 | PGDB_AS001008 | View |
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A017412 | PGDB_C001355 | PGDB_AS000601 | View |
| % Degradation | - | = | 50-70 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A019398 | PGDB_C001355 | PGDB_AS002288 | View |
| GI50 | - | = | 0.1-1 | uM | - | — | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A020940 | PGDB_C001355 | PGDB_AS001887 | View |
| % Degradation | - | = | 50-70 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A043592 | PGDB_C001355 | PGDB_AS001067 | View |
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A062115 | PGDB_C001355 | PGDB_AS001994 | View |
| GI50 | - | = | 0.1-1 | nM | - | — | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A066230 | PGDB_C001355 | PGDB_AS000013 | View |
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A076153 | PGDB_C001355 | PGDB_AS001448 | View |