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Compound
PGDB_C001305
8 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)n4ncc5ccccc54)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A010469 | PGDB_C001305 | PGDB_AS000601 | View |
| Relative binding | Ctrl @ 5uM | < | 0.1 | % | 5 uM | 1 h | CRBN | CRBN | HEK293 | WO2025110699A1 | PGDB_A014146 | PGDB_C001305 | PGDB_AS001966 | View |
| Relative binding | Ctrl @ 5uM | < | 0.1 | % | 5 uM | 1 h | CRBN | CRBN | HEK-293 | KR20250075510A | PGDB_A021182 | PGDB_C001305 | PGDB_AS000026 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A058065 | PGDB_C001305 | PGDB_AS001448 | View |
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A058240 | PGDB_C001305 | PGDB_AS001008 | View |
| % Degradation | - | = | 30-50 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A058515 | PGDB_C001305 | PGDB_AS001067 | View |
| % Degradation | - | = | 30-50 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A065296 | PGDB_C001305 | PGDB_AS002288 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A067841 | PGDB_C001305 | PGDB_AS001994 | View |