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Compound
PGDB_C000458
6 activity records3 related patents
2D structure
N#Cc1ccc(C2CN(C3CCCCC3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | CN117836288A | PGDB_A008144 | PGDB_C000458 | PGDB_AS002458 | View |
| EC50 | - | = | 0.031 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A014520 | PGDB_C000458 | PGDB_AS001696 | View |
| EC50 | - | = | 0.031 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A018559 | PGDB_C000458 | PGDB_AS001482 | View |
| EC50 | - | = | 0.031 | uM | - | — | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A046054 | PGDB_C000458 | PGDB_AS001328 | View |
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | - | HEK293T | US20230265071A1 | PGDB_A053584 | PGDB_C000458 | PGDB_AS000278 | View |
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A066928 | PGDB_C000458 | PGDB_AS000416 | View |