Assay

PGDB_AS002338

System: cell_basedTarget: IKZF1Cell line: NCI-H929
Assay context summary

Assay context

10 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF1
E3Not specified
Cell lineNCI-H929
Detection targetprotein_degradation
Activity compounds and values

Activity records

10 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C025617
DC50-=0.077nM-—IKZF1-NCI-H929CA3286762A1PGDB_A008513PGDB_C025617PGDB_AS002338View
2D structure for PGDB_C025599
DC50-=0.081nM-—IKZF1-NCI-H929CA3286762A1PGDB_A011550PGDB_C025599PGDB_AS002338View
2D structure for PGDB_C025601
DC50-=0.23nM-—IKZF1-NCI-H929CA3286762A1PGDB_A018532PGDB_C025601PGDB_AS002338View
2D structure for PGDB_C021276
DC50-=0.34nM-—IKZF1-NCI-H929CA3286762A1PGDB_A020207PGDB_C021276PGDB_AS002338View
2D structure for PGDB_C025616
DC50-=0.1nM-—IKZF1-NCI-H929CA3286762A1PGDB_A031045PGDB_C025616PGDB_AS002338View
2D structure for PGDB_C025615
DC50-=8.86nM-—IKZF1-NCI-H929CA3286762A1PGDB_A046563PGDB_C025615PGDB_AS002338View
2D structure for PGDB_C025597
DC50-=0.31nM-—IKZF1-NCI-H929CA3286762A1PGDB_A050550PGDB_C025597PGDB_AS002338View
2D structure for PGDB_C025600
DC50-=0.38nM-—IKZF1-NCI-H929CA3286762A1PGDB_A065101PGDB_C025600PGDB_AS002338View
2D structure for PGDB_C021277
DC50-=0.37nM-—IKZF1-NCI-H929CA3286762A1PGDB_A067353PGDB_C021277PGDB_AS002338View
2D structure for PGDB_C025619
DC50-=0.98nM-—IKZF1-NCI-H929CA3286762A1PGDB_A067568PGDB_C025619PGDB_AS002338View
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