PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

49 activity records

Assay family% Degradation

Systemcell_based

Readoutpercent_remaining

TargetMYC

E3Not specified

Cell lineHL-60

TechnologyWestern_blot

Activity compounds and values

Activity records

49 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	57	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A007749	PGDB_C000579	PGDB_AS002563	View
% Degradation	-	=	89	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A008939	PGDB_C000621	PGDB_AS002563	View
% Degradation	-	=	83	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A009657	PGDB_C000540	PGDB_AS002563	View
% Degradation	-	=	5	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A009713	PGDB_C001985	PGDB_AS002563	View
% Degradation	-	=	81	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A009808	PGDB_C000559	PGDB_AS002563	View
% Degradation	-	=	93	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A015587	PGDB_C000616	PGDB_AS002563	View
% Degradation	-	=	-57	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A016640	PGDB_C000632	PGDB_AS002563	View
% Degradation	-	=	100	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A018060	PGDB_C000629	PGDB_AS002563	View
% Degradation	-	=	91	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A018716	PGDB_C000558	PGDB_AS002563	View
% Degradation	-	=	92	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A021303	PGDB_C000619	PGDB_AS002563	View
% Degradation	-	=	77	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A023392	PGDB_C000594	PGDB_AS002563	View
% Degradation	-	=	77	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A025079	PGDB_C000568	PGDB_AS002563	View
% Degradation	-	=	100	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A026809	PGDB_C000610	PGDB_AS002563	View
% Degradation	-	=	74	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A028890	PGDB_C000606	PGDB_AS002563	View
% Degradation	-	=	100	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A030951	PGDB_C000557	PGDB_AS002563	View
% Degradation	-	=	50	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A033048	PGDB_C000612	PGDB_AS002563	View
% Degradation	-	=	81	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A035834	PGDB_C000555	PGDB_AS002563	View
% Degradation	-	=	-5	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A036904	PGDB_C002015	PGDB_AS002563	View
% Degradation	-	=	97	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A037097	PGDB_C000644	PGDB_AS002563	View
% Degradation	-	=	90	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A037276	PGDB_C000604	PGDB_AS002563	View

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