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Compound
PGDB_C000540
9 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(CNCC4CCN(c5ncc(-c6cccc7ccccc67)cn5)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 83 | % | 10 nM | 24 h | MYC | - | HL-60 | WO2023116835A1 | PGDB_A009657 | PGDB_C000540 | PGDB_AS002563 | View |
| IC50 | - | = | 2 | nM | - | — | - | - | HL-60 | CN117982498A | PGDB_A017111 | PGDB_C000540 | PGDB_AS001350 | View |
| % Degradation | - | = | 73 | % | 10 nM | 24 h | CSNK1A1 | - | HL-60 | WO2023116835A1 | PGDB_A021282 | PGDB_C000540 | PGDB_AS000414 | View |
| % Degradation | - | = | 84 | % | 10 nM | 24 h | GSPT1 | - | HL-60 | WO2023116835A1 | PGDB_A026913 | PGDB_C000540 | PGDB_AS000871 | View |
| % Degradation | - | = | 84 | % | 10 nM | 24 h | - | - | HL-60 | CN117982498A | PGDB_A043385 | PGDB_C000540 | PGDB_AS001212 | View |
| % Degradation | - | = | 55 | % | 10 nM | 24 h | IKZF2 | - | HL-60 | WO2023116835A1 | PGDB_A050612 | PGDB_C000540 | PGDB_AS000166 | View |
| % Degradation | - | = | 55 | % | 10 nM | - | IKZF2 | - | - | CN117982498A | PGDB_A053904 | PGDB_C000540 | PGDB_AS002235 | View |
| % Degradation | - | = | 73 | % | 10 nM | 24 h | - | - | HL-60 | CN117982498A | PGDB_A071352 | PGDB_C000540 | PGDB_AS000728 | View |
| % Degradation | - | = | 83 | % | 10 nM | - | - | - | HL-60 | CN117982498A | PGDB_A074672 | PGDB_C000540 | PGDB_AS001270 | View |